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ADDERALL-XR (AMPHETAMINE, DEXTROAMPHETAMINE): DOSAGE AND ADMINISTRATION

Dosing Considerations for all Patients

Individualize the dosage according to the therapeutic needs and response of the patient. Administer Adderall-XR capsules at the lowest effective dosage.

Based on bioequivalence data, patients taking divided doses of immediate-release Adderall tablets, (for example, twice daily), may be switched to Adderall-XR (Amphetamines with Dextroamphetamines) at the same total daily dose taken once daily. Titrate at weekly intervals to appropriate efficacy and tolerability as indicated.

Adderall-XR extended release capsules may be taken whole, or the capsule may be opened and the entire contents sprinkled on applesauce. If the patient is using the sprinkle administration method, the sprinkled applesauce should be consumed immediately; it should not be stored. Patients should take the applesauce with sprinkled beads in its entirety without chewing. The dose of a single capsule should not be divided. The contents of the entire capsule should be taken, and patients should not take anything less than one capsule per day.

Adderall-XR (Amphetamines with Dextroamphetamines) may be taken with or without food.

This medication should be given upon awakening. Afternoon doses should be avoided because of the potential for insomnia.

Where possible, Amphetamine with Dextroamphetamine (Adderall-XR) therapy should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy.

Children

In children with ADHD who are 6-12 years of age and are either starting treatment for the first time or switching from another medication, start with 10 mg once daily in the morning; daily dosage may be adjusted in increments of 5 mg or 10 mg at weekly intervals. When in the judgment of the clinician a lower initial dose is appropriate, patients may begin treatment with 5 mg once daily in the morning. The maximum recommended dose for children is 30 mg/day; doses greater than 30 mg/day of Amphetamines and Dextroamphetamines (Adderall-XR) have not been studied in children. This drug has not been studied in children under 6 years of age.

Adolescents

The recommended starting dose for adolescents with ADHD who are 13-17 years of age and are either starting treatment for the first time or switching from another medication is 10 mg/day. The dose may be increased to 20 mg/day after one week if ADHD symptoms are not adequately controlled.

Adults

In adults with ADHD who are either starting treatment for the first time or switching from another medication, the recommended dose is 20 mg/day.



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